Forum Topic: new topic: shRNA Clones

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new topic: shRNA Clones

shRNA is a sequence of RNA which makes a tight hairpin turn that can be used to silence target gene expression via RNAi. Expression of shRNA in cells is typically accomplished by delivery of plasmids or through viral or bacterial vectors. Compared to siRNA, shRNA offers benefits in silencing longevity, delivery options, and cost. Expressed shRNA is transcribed in cells from a DNA template as a single-stranded RNA (ssRNA) molecule (~50 – 100 bases). Complementary regions spaced by a small 'loop' cause the transcript to fold back on itself forming a 'short hairpin' in a manner analogous to natural microRNA. Recognition and processing via the RNAi machinery convert the shRNA into the corresponding siRNA. [url]https://www.creative-biogene.com/products/shrna-clones.html[/url]

This topic was started by Mia Chou.
Posted by on 2021-11-17 09:41:10
 
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