Forum Topic: PNA Backbone Modification

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PNA Backbone Modification

Since the PNA was proposed, chemical modification of its structural units has become one of the research focuses. In the modification of PNA structural unit, backbone modification is the main measure to improve the transport performance of PNA cells. The backbone modification refers to the modification of the N-(2-aminoethyl) glycine unit structure of the PNA. The backbone modification PNA has achieved certain success in increasing the water solubility and enhancing the hybridization performance. Moreover, partial backbone modified PNAs also have special advantages such as optical properties and self-assembly, which expand the application range of PNAs. [url][/url]

This topic was started by Caroline Miller.

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