Forum Topic: Frequently Asked Questions About Human Genome Sequencing Project

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Frequently Asked Questions About Human Genome Sequencing Project

What is a genome? A genome is a complete deoxyribonucleic acid (DNA) of an organism, a compound containing genetic instructions needed to develop and direct each biological activity. A DNA molecule consists of two twisting, paired strands. Each strand consists of four chemical units called nucleotide bases. The bases are adenine (A), thymine (T), guanine (G) and cytosine (C). The basis of the opposite strand is specific; A is always paired with T, and C is always paired with G. The human genome contains approximately 3 billion of these base pairs, which are located in 23 pairs of chromosomes in the nucleus of our cells. Each chromosome contains hundreds to thousands of genes with instructions for making proteins. Each of the estimated 30,000 genes in the human genome produces an average of three proteins. What is Human Genome Sequencing and how to sequence the genome? Human Genome Sequencing, which means determining the exact sequence of base pairs in a DNA fragment. Human chromosomes range in size from about 50,000,000 to 300,000,000 base pairs. Because bases exist in pairs, and the identity of one base in the pair determines another member of the pair, scientists don’t have to report the two bases of the pair. More on the

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