Forum Topic: Fosmid Library Construction

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Fosmid Library Construction

The fosmid system has been widely used in the construction of large-insert genomic libraries. Fosmid clones are similar in insert size comparing with cosmid clones and smaller than that in BAC and yeast artificial chromosomes (YAC). Based on E. coli F-plasmids, the single copy of fosmid clones exists in the host bacteria, and maintains high stability through 160 generations of monoclonal subculture.

This topic was started by wendy wilson.

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