Forum Topic: CD200

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CD200/CD200R-signaling increases the threshold for immune activation and is known to be vital for restraining inflammatory responses. On the contrary, CD200 expression on tumor cells is a marker for disease progression, suggesting a role in suppression of anti-tumor responses. CD200/CD200R1 signaling has been implicated in a number of immune-related diseases such as allergic disorders, infection, arthritis, transplantation, and autoimmune disorders such as multiple sclerosis and systemic lupus erythematosus.

This topic was started by wendy wilson.

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