Forum Topic: Viral Genome Sequencing

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Viral Genome Sequencing

Viruses are the most abundant biological entities on Earth and significantly impact living organisms by causing diseases and shaping their immune systems. Despite their ubiquity and influence, less than 0.01% of viruses are sequenced. Presently, the study of viral infectious diseases in terms of etiopathogenesis and development of newer therapeutics is undergoing rapid changes. One commonly used NGS platforms: Illumina, recommend maximum fragment lengths of about 300-500 nucleotides for analysis respectively. More recently sequencing technology has been improved with PacBio single-molecule real-time sequencing. Here complete long reads can be obtained with less error overcoming a limitation of the NGS. CD genomics platform holds great potential for viral genome sequencing. A comprehensive virus sequences will facilitate interpretation of metagenomic data by providing reference genomes, lead to a better understanding of virus diversity, ecology, adaptation and evolution, and enable the prediction of emerging infectious diseases caused by viruses. Source:

This topic was started by Kiko Garcia.

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