Forum Topic: In Vitro Mammalian Chromosomal

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In Vitro Mammalian Chromosomal

Creative Bioarray provides in vitro mammalian chromosomal aberration test (OECD 473) to identify substances that cause structural chromosomal aberrations in cultured mammalian cells (Chinese Hamster Ovary cell line CHO-K1, other cells upon request). This assay is available under either GLP (Good Laboratory Practice) or Non-GLP conditions. Many human genetic diseases are caused by chromosomal aberrations. Chromosomal damages in somatic cells that involve alterations in oncogenes and tumor suppressor genes are also related to tumor formation in humans and animals. Therefore, in vitro mammalian chromosomal aberration test is one of the recommended in vitro tests for mutagen assessment. https://www.creative-bioarray.com/Services/in-vitro-mammalian-chromosomal-aberration-test-oecd-473.htm

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