Forum Topic: Quantitative Tissue Distribution

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Quantitative Tissue Distribution

Tissue distribution of drugs in the body is a feature that can determine the overall efficacy of new therapeutic compounds and imaging agents. In order to obtain an effective concentration of therapeutic compounds in the target tissue, therapeutic compounds should exudate from the circulating blood to the target tissue or accumulate nonspecifically, binding to the molecular target. Tissue distribution parameters contribute to risk assessment of compounds, including targeting efficiency, off-target accumulation, and prediction of potential sites of adverse reactions. Creative Bioarray designed and implemented quantitative whole-body autoluminescence (QWBA) services in accordance with GLP standards, which can rapidly quantify tissue distribution in various animal models. Besides, we can also combine with preclinical DMPK services to obtain high-resolution images and provide greater depth and detail distribution in tissues or target organs. https://www.creative-bioarray.com/services/quantitative-tissue-distribution.htm

This topic was started by Hannah Cole.
Posted by on 2020-09-10 09:31:19
 
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Posted by on 2020-09-10 09:32:00
 
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