Forum Topic: Coumarin

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The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in natural products such as tonka beans, warfarin, and clover leaf, displays interesting pharmacological properties. The parent molecule was first isolated by Vogel from tonka beans. The coumarin ring can be looked upon as arising out of a fusion of a pyrone ring with a benzene nucleus. The derivatives of coumarin usually occur as secondary metabolites present in seeds, roots, and leaves of many plant species. More than 300 coumarins have been identified from natural sources, especially from green plants. These varying substances have disparate pharmacological, biochemical, and therapeutic applications. As for physical properties, coumarin is a white crystalline, volatile compound. It smells like vanilla and has a melting point of 341-344 K.

This topic was started by Alex Brown.

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