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Hello students,

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Microbiosci offers a technology package when we are doing the technology transfer and technology commercialization. The technology package includes: Technological know-how documents, strains, on-site technical support, lab scale demonstration (pilot scale demonstration and industrial, when necessary). From lab scale to industrial scale, our fermentation professionals will provide sufficient technical assistance to assure that each technology will be well absorbed by the end user.

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Calcium channel have been well recognized as therapeutic targets for treating a number of diseases. However, the calcium channel class is considered to be underexploited due to the lack of reliable functional cell-based assays for high-throughput screening.

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In vivo imaging can achieve long-term tracking of individual organisms, improve the comparability of experimental data, and provide the most direct evidence of individual organisms. Bioluminescence and fluorescence techniques are mainly used in vivo optical imaging of living animals.

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The outbreak of COVID-19 has highlighted the importance of proper hygiene. The prevalence of the pandemic is mainly a result of the virus’s transmission method. The virus can spread easily through respiratory droplets, which can stay on surface or in the air for a while. CDC suggests a few ways to prevent virus spreading including keeping social distance, wash hand frequently and clean/disinfectant surface routinely.

As a chemical supplier, BOC Sciences has been trying hard to streamline the production of the current necessities like disinfectants. We here provide a list of products that could be used in different formulations for disinfectants, hand sanitizers and other cleaning products. We have secured stable source for these products and hope to help more customers to continue their production and supply the community with the essential needs.

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Microbiosci specializes in providing comprehensive and advanced amino acid fermentation technologies. Microbiosci has successfully been using an expanded downstream process for the past ten years. It has led to significant improvements in product yields, productivity, production costs, and environmental performance.

https://microbiosci.creative-biogene.com/amino-acid-fermentation.html
The transfer of electrons among molecules is essential to all organisms, microbes are no exception, for this process generates energy by which they need to survive. While some microorganisms living in oxygen-deprived environments have evolved a unique form of breathing that involves excreting and pumping out electrons, have the potential to act as electricity-producing components that can be used in microbial fuel cells (MFCs), which can be put into use of contributing energy.

https://microbiosci.creative-biogene.com/microbial-fuel-cell-service.html
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Microbial oil, also known as single cell oil, is generally extracted from some yeast, molds, microalgae and bacteria, which utilize carbohydrate, hydrocarbon and/or ordinary grease as carbon sources and produce oil and/or lipids with commercial value. Due to its higher degree of unsaturation than animal and vegetable oil, microbial oil is even more qualified as the source of biodiesel.

https://microbiosci.creative-biogene.com/microbial-oil-production.html
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Bioenergy derived from biomass plays a more and more significant role in today’s energy supply system due to its renewability and sustainability. Biomass is the term referring to the material that we harness from organisms to use as biofuel, as well as the social, technical, scientific and economic fields benefited by biological sources. The wide distribution of biomass provides rich sources of energy generating raw materials. Exploiting clean and renewable microbial sourced energy is a particularly promising approach, which is efficient and eco-friendly in producing biofuel, heat and electricity via various routes including thermo-chemical, biological, and bio-electrochemical processes.

https://microbiosci.creative-biogene.com/microbial-energy.html
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Microbiosci is a major manufacturer and supplier of biotechnology around the world for diversified industries. Microbiosci specializes in providing comprehensive and advanced microbial fermentation technologies.

https://www.creative-biogene.com/microbiosci/microbial-industry-fermentation-technology.html
Acroscell provides QT prolongation assay using isolated heart (Langendorff Assay) to evaluate the cardiotoxicity of compounds with QT interval as the indicator. The potential to prolong the QT interval has a major impact on drug development programs. A rapid, inexpensive, reproducible and sensitive predictions of QT-prolonging potential can be provided by isolated heart preparation by Langendorff preparation.

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Insulin is a hormone that regulates the amount of glucose in the blood and is required for the body to function normally. The gene that codes for the production of insulin is located in the short arm of chromosome 11. It has a total of 51 amino acids and 2 polypeptide chains called A and B. Insulin is produced by cells in the pancreas, called the islets of Langerhans. These cells continuously release a small amount of insulin into the body, but they release surges of the hormone in response to a rise in the blood glucose level.

https://www.creative-biogene.com/microbiosci/insulin-fermentation.html
Echinacoside, a natural polyphenolic compound, has various kinds of pharmacological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. https://www.bocsci.com/echinacoside-cas-82854-37-3-item-2980.html
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The services for modification of interleukin genes and optimization of expressing are also available. Prominent examples are well presented such as: Modifying the gene coding sequence and optimizing the Shine-Dalgarno sequence in the gene promoter region to increase the protein expression level significantly; Recombinant DNA technology could also be used in chiming interleukin genes with other protein genes, to express the fusion protein with activeness and/or advantages of both proteins; Point mutation could also be arranged to obtain interleukins with higher stability and biological activity.

https://microbiosci.creative-biogene.com/recombinant-interleukin-production.html
Antibiotics are a type of drugs or medicines that hinder the growth of bacteria. Generally, they kill the microorganisms and also cure bacterial infections. Any drug that kills any microorganism or germ is known as antibiotics. The first-ever antibiotics discovered was Penicillin. So far, over 4500 different antibiotics have been recorded, but only some 100 have been widely used to treat human, animal and plant diseases. The genus Streptomyces is the source of more than one half of the known antibiotics, the other being derived from Micromonospora, Actinoplanes Nocardia, Actinomadura, Bacillus, and few other microbes.

https://www.creative-biogene.com/microbiosci/antibiotics-fermentation.html
Due to economic and environmental advantages as well as to the development of new genetic engineering techniques, the fermentation is the most used process at industrial scale. Several studies involving mutagenesis and metabolic engineering approaches have been applied to aim to improve amino acid producing strains and thereby enhance amino acid productivity and expand the spectrum of products and feedstocks for fermentation.

https://www.creative-biogene.com/microbiosci/amino-acid-fermentation.html
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https://www.creative-biogene.com/microbiosci/products/amino-acid-fermentation.html
Microbiosci is the premier institution offering professional and comprehensive somatropin production services. We have years of experience to add value to your research and manufacturing. Like any other recombinant protein production services, we offer the full service of manufacturing somatropin with advanced genetic tools and fermentation techniques. The somatropin gene is reverse-transcribed from the mRNA found in pituitary glands before inserting into plasmid. Then the recombinant plasmids are transferred into bacteria, in most cases, Escherichia coli. After the construction of strains, the optimization of fermentation condition will be performed to ensure quality and productivity of the production.

https://microbiosci.creative-biogene.com/somatropin-production.html
Histological staining is often used to provide visibility into specific biological tissues. This technique can help us to better conduct molecular biology research. Creative Bioarray provides a series of histological staining methods and related products to help our clients achieve the best dyeing purposes. Our team is always committed to providing customers with high quality products and services.

https://www.creative-bioarray.com/products/histological-stains-dyes-list-425.htm
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Bellidifolin is a xanthone that can be isolated from the plants of Gentiana species. Study shows that bellidifolin is a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Bellidifolin may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms related to inhibition of cell apoptosis independent of the ERK pathway, but may involve blockade of p38MAPK signaling pathway activation and downstream caspase-3 expression. https://www.bocsci.com/bellidifolin-cas-2798-25-6-item-177976.html
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JULIET S

 
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Microbiosci offers a technology package when we are doing the technology transfer and technology commercialization. The technology package includes: Technological know-how documents, strains, on-site technical support, lab scale demonstration (pilot scale demonstration and industrial, when necessary). From lab scale to industrial scale, our fermentation professionals will provide sufficient technical assistance to assure that each technology will be well absorbed by the end user.

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Microbiosci provides the most advanced facilities and expertise to accelerate the development, demonstration and commercialization of microbial technologies.

https://microbiosci.creative-biogene.com/insulin-fermentation.html
Microbiosci provides comprehensive microbial fermentation services to support research, process development, preclinical studies, and phase I clinical trials. Our statins are produced by a variety of filamentous fungi including Penicillium species, Monascus ruber and Aspergillus terreus as a secondary metabolite.

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By combining the advanced genetic tools with optimal screening techniques, Microbiosci can assist you to reprogram microbes and create mutations with high commercial value – optimizing strains to ensure their sustainability, maximize converting efficiency and minimize costs.

https://microbiosci.creative-biogene.com/microbial-energy.html
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Microbial production is commercially feasible for several vitamins, such as vitamin B2, vitamin B6, vitamin B12 and vitamin C. Fermentation technologies provide an alternative to chemical processes in the production of wide range vitamins from microbes.

https://microbiosci.creative-biogene.com/vitamins-fermentation.html
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In the manufacturing process of a vaccine, one or several genes of etiologic agents have been cloned, expressed and purified to be developed as vaccines. There are a variety of expression systems with different advantages such as bacteria, yeast, mammalian cells and insect cells, allowing the production of large quantities of proteins depending on the required characteristics, which would stimulate the immune system in a way similarly to bearing natural infections. And the vaccines can be put into use for both prophylactic and therapeutic.

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Acroscell CiPA service provides you with a robust cost-effective approach to determine cardiac risk, earlier in your program and with turnaround times that support your lead discovery and optimization pipeline.

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Liver diseases occur frequently and are life-threatening for humans. The underlying causes vary from viral infections, autoimmune diseases and intoxications (including alcohol abuse) to unbalanced diets. Although the liver can regenerate without injury in the early stages of the disease, it cannot heal in the later stages and may require an organ transplant. We must understand the underlying mechanisms in order to design and develop new drugs in this area. Mature and stable animal models to mimic human liver diseases could thus play an important role.

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Acroscell provides multiple tissues for test: isolated ventricular strips, trabeculae, papillary muscle, Purkinje fibres or cardiomyocytes. Since Purkinje fibers are thought to be an important site for initiation of arrhythmias, here we give an example of Purkinje fibers.

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MFCs is a brilliant tool for wastewater treatment, meanwhile, pathogens can also be reduced, which is a quite promising field in ecological restoration. Moreover, MFCs can work as biosensors to measure the solute concentration of wastewater, online monitoring can be realized as to BOD, COD, DO, toxics, etc.

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Microbiosci specializes in providing comprehensive and advanced organic acid fermentation technologies. A careful strain selection for a specific organic acid production is very important.

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Sodium channels are that form ion channels, conducting sodium ions (Na+) through cellular plasma membrane. Voltage-gated sodium channels (also called "VGSCs" or "Nav channel") are present in the membrane of most excitable cells and are involved in many cardiac or neuronal diseases.

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Microbial oil, also known as single cell oil, is generally extracted from some yeast, molds, microalgae and bacteria, which utilize carbohydrate, hydrocarbon and/or ordinary grease as carbon sources and produce oil and/or lipids with commercial value. Due to its higher degree of unsaturation than animal and vegetable oil, microbial oil is even more qualified as the source of biodiesel.

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Microbiosci is a major manufacturer and supplier of biotechnology around the world for diversified industries. Microbiosci specializes in providing comprehensive and advanced microbial fermentation technologies, such as nutrition, vitamins, amino acid, immune suppresser, antibiotics, pesticides, antiseptic, statins, steroids, antidiabetic, anti-obesity, industrial enzymes, organic acid, bio-energy. As a global leader, Microbiosci is dedicated to technology transfer and technology commercialization for microbial fermentation technologies in the field of bio-energy, especially for bio-pharmaceuticals, bio-energy, bio-pesticide, bio-agriculture, waste treatment, feedstuffs and food additives, etc.

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Microbiosci is involved in R&D, technology transfer and technology commercialization for industrial fermentation technologies in the area of bio-pharmaceuticals, especially for A. P. I., bio-pesticide, bio-agriculture, feedstuffs and food additives. Additionally, Microbiosci offer a technology package when we are doing the technology transfer.

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Started by:
Lukas Mueller
2020-09-18 13:05:35
 
This topic contains release notes for new SGN website features.
Started by:
riiupw afrass
2020-09-18 01:11:55
 
What You'll Learn in This Article
Results of studies examining addictive potential of CBD
Hemp-derived CBD vs marijuana-derived CBD
CBD and THC, the entourage effect
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CBD and prescription drug interactions
There's a growing amount of research pointing out the benefits of CBD. Studies have shown that CBD provides anti-inflammatory and seizure-suppressant properties, as well as the ability to reduce social anxiety.

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Goose Washington
2020-09-17 16:17:20
 
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Started by:
Sridhar Gutam
2020-09-17 11:00:50
 
Dear All,

I would like to work on phenotyping tomato and brinjal (egg plant) for abiotic stress tolerance traits. For that I would like to know what are the materials and methods needed.

Why I am asking is that if any one in the community had developed a set of protocols for low cost phenotyoing, i would like to use it.

Please connect me with people who are working on phenotyping tomato.

Thanks
Sridhar
Started by:
max smith
2020-09-17 10:47:33
 
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César Benavidez
2020-09-17 09:12:00
 
Dear friends, I am about to begin an investigation of lycopene content in tomato species, as well as identification of microsatellites to identify the gene or genes responsible for the character under study, so I ask if I could help with information on the research topic . Thank you very much
Started by:
wendy wilson
2020-09-17 05:18:15
 
https://www.creative-biogene.com/microbiosci/products/antibiotics-fermentation.html
2020-09-17 02:54:11
 
Hi dears,
Is there any possibility that someone can share the cDNA library of benthamiana? Please let me know, if it is possible. Thanks.
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Hi, I would like to know if there is a straightforward way to translate the one nomenclature to the other.
Both refer to genes/loci/protein, right... but if I have to compare to see coincidences from one list in one format and one list in the other (having hundreds of proteins/genes in each list), I can die doing searches and endless alignments, and still not accomplishing the job...
Please help.
Thank you very much.
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Started by:
Erwin Aragon
2020-09-15 16:21:14
 
Dears friends: I want to Know if Are there microsatellite or other molecular marker that can be used for identify differents species in tomato??? i mean between sculentum and
Started by:
riiupw afrass
2020-09-15 09:09:26
 
Started by:
john binns
2020-09-15 04:30:49
 
This topic is for members of the SOL community from around the world to publish job openings. If interested, please reply directly to the poster. Job postings submitters please note that the postings will be removed by default 8 months after posting.
Started by:
Emilio Ortiz
2020-09-15 03:34:36
 
Hi,

Is there any way to download the 2860 COSII sequences? Please let me know.


Thank you,
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Henry Joans
2020-09-14 05:49:55
 
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Started by:
Lukas Mueller
2020-09-14 03:42:58
 
In the next few years, hundreds of Solanaceae will be sequenced using next generation sequencing methods. If you intend to sequence a Solanaceae, please provide information on the species to avoid duplicate sequencing of accessions on the SGN SOL-100 page http://solgenomics.net/organism/sol100/view. This topic is for the discussion of SOL-100 related questions.
Started by:
Anais Merreta
2020-09-14 01:49:15
 
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chelsea clark
2020-09-13 09:56:04
 
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Started by:
wendy wilson
2020-09-13 07:49:31
 
https://www.creative-biogene.com/microbiosci/products/pesticides-386.html
Started by:
Hannah Cole
2020-09-12 06:24:42
 
Creative Bioarray provides in vitro mammalian chromosomal aberration test (OECD 473) to identify substances that cause structural chromosomal aberrations in cultured mammalian cells (Chinese Hamster Ovary cell line CHO-K1, other cells upon request). This assay is available under either GLP (Good Laboratory Practice) or Non-GLP conditions.

Many human genetic diseases are caused by chromosomal aberrations. Chromosomal damages in somatic cells that involve alterations in oncogenes and tumor suppressor genes are also related to tumor formation in humans and animals. Therefore, in vitro mammalian chromosomal aberration test is one of the recommended in vitro tests for mutagen assessment.

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2020-09-08 12:27:20
 
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2020-09-08 08:24:04
 
Organic acids are among the most versatile ingredients in the food and beverage industry because of their three main properties: they are soluble, hygroscopic, and have the abilities of buffering and chelation. Due to their wide applications in the food industry as additives and as chemical feedstocks, there is an increasing demand for organic acid production.

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2020-09-06 09:19:34
 
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Peng Wang
2020-09-05 03:40:57
 
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Naama Menda
2020-09-02 08:01:29
 
This topic discusses issues in developing controlled-vocabularies for describing Solanaceae phenotypes and traits.
Most should be covered by the 'Solanaceae Phenotype Ontology' (SPO)
(see SGN->Tools->Ontology browser) which is growing by demand of its users community.
Terms which exist in other ontologies (PO, PATO, etc) are mapped to SPO terms.
In some cases it will be advised to use other vocabularies, instead of providing new SPO terms.
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Hello
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Example in PGSC annotation available in Phytozome

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optimus optimus
2020-09-02 06:17:45
 
Hi,
I am very confused browsing literature because I can not find a clear statement about the ploidy of N. benthamiana.
N. tabacum is clearly an allotetraploid, and tetraploid (2n = 4x = 48), with 4 copies of n=12. Genome size over 4.5 Gb, however,
N benthamiana it is reported to be an "ancient" allotetraploid, but currently it is n=19, and 38 total number of chromosomes, so it seems that from the ancient allotetraploid (48 chromosomes), genome fractionation has occurred and 38 remains, and that currently the genome is "diploid" (2n = 2x = 38). Is this correct?. Is N benthamiana diploid?.
Thank you very much.
Best regards,
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This topics is for the researchers of the SOL community around the world who need some specific materials for their experiments and express some request to those who could provide them with the expected materials or resources.
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Mark Johnson
2020-08-24 04:19:20
 
Dear Sol genomics network,

Shin-Han Shiu, Marja Timmermans, and I are organizing this summer's Cold Spring Harbor "Frontiers and Techniques in Plant Sciences" (June 27 - July 17).

The course provides foundational work in plant sciences as well as practical laboratory experience in techniques like RNA-seq, proteomics, mapping-by-sequencing, genome editing, and imaging. In recent years the course has stressed the quantitative nature of plant biology and students will be introduced to computational techniques required for analyzing large datasets.

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APPLICATIONS ARE DUE APRIL 15.

Thank you,

Mark Johnson
Brown University
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This topic contains release notes for new SGN data releases.
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Media by Mojang via Giphy 3rd party content, see our FAQ
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Image by Minecraft
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Minecraft Ghast is a cat
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Image by Minecraft
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Enough chatting – let’s get to the money-making ideas.

17 ways to make money from your #blog - #monetization
CLICK TO TWEET
How to make money blogging in 2020
Before I jump into the ideas, let me just give you a quick rundown of how I’m going to be ordering them. I’ll start with the most popular monetization methods and slowly get more narrow as the list goes on. So if you’re already familiar with the basics of how to make money with a blog, you might be able to skip the first few suggestions. Otherwise, start at the beginning!

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Our own affiliate program here at ThemeIsle. Check the details here.
A list of the top WordPress-related affiliate programs in the market.
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riiupw afrass
2020-03-18 11:22:13
 
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