GO:0004708 'MAP kinase kinase activity'
| Cvterm details |
| Term id | GO:0004708 |
| Term name | MAP kinase kinase activity |
| Term definition | Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate. |
| Comment |
Synonyms
MAPKK1 RELATED EC:2.7.12.2
MEK activity BROAD
MEK1 RELATED EC:2.7.12.2
MEK2 RELATED EC:2.7.12.2
ATP:protein phosphotransferase (MAPKKK-activated) activity EXACT EC:2.7.12.2
ERK activator kinase activity EXACT
MAP kinase kinase 4 activity NARROW EC:2.7.12.2
MAP kinase kinase 7 activity NARROW EC:2.7.12.2
MAP kinase or ERK kinase activity RELATED EC:2.7.12.2
MAP2K RELATED EC:2.7.12.2
MAPKK RELATED EC:2.7.12.2
MAPKK activity EXACT
mitogen-activated protein kinase kinase activity EXACT EC:2.7.12.2
MKK RELATED EC:2.7.12.2
MKK2 RELATED EC:2.7.12.2
MKK4 RELATED EC:2.7.12.2
MKK6 RELATED EC:2.7.12.2
MKK7 RELATED EC:2.7.12.2
STK27 RELATED EC:2.7.12.2
"ATP:protein phosphotransferase (MAPKKK-activated) activity" EXACT [EC:2.7.12.2]
"ERK activator kinase activity" EXACT []
"MAP kinase kinase 4 activity" NARROW [EC:2.7.12.2]
"MAP kinase kinase 7 activity" NARROW [EC:2.7.12.2]
"MAP kinase or ERK kinase activity" RELATED [EC:2.7.12.2]
"MAP2K" RELATED [EC:2.7.12.2]
"MAPKK" RELATED [EC:2.7.12.2]
"MAPKK activity" EXACT []
"MAPKK1" RELATED [EC:2.7.12.2]
"MEK activity" BROAD []
"MEK1" RELATED [EC:2.7.12.2]
"MEK2" RELATED [EC:2.7.12.2]
"mitogen-activated protein kinase kinase activity" EXACT [EC:2.7.12.2]
"MKK" RELATED [EC:2.7.12.2]
"MKK2" RELATED [EC:2.7.12.2]
"MKK4" RELATED [EC:2.7.12.2]
"MKK6" RELATED [EC:2.7.12.2]
"MKK7" RELATED [EC:2.7.12.2]
"STK27" RELATED [EC:2.7.12.2]
"MAPKK" RELATED [EC:2.7.12.2, PMID:20811974]
Definition dbxrefs
Related dbxrefs
EC:2.7.11.-
MetaCyc:2.7.12.2-RXN
Reactome:REACT_21301 "Activation of p38 alpha/beta MAPK, Homo sapiens"
Reactome:REACT_21350 "Activation of p38 alpha/beta MAPK, Mus musculus"
Reactome:REACT_75807 "Activation of p38 MAPK, Homo sapiens"
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