Term id	GO:0004722
Term name	protein serine/threonine phosphatase activity
Term definition	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
Comment

Synonyms
3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase NARROW EC:3.1.3.16
Aspergillus awamori acid protein phosphatase NARROW EC:3.1.3.16
BCKDH phosphatase NARROW EC:3.1.3.16
branched-chain alpha-keto acid dehydrogenase phosphatase NARROW EC:3.1.3.16
calcineurin NARROW
casein phosphatase NARROW EC:3.1.3.16
HMG-CoA reductase phosphatase NARROW EC:3.1.3.16
phosphatase 2A NARROW EC:3.1.3.16
phosphatase 2B NARROW EC:3.1.3.16
phosphatase C-II NARROW EC:3.1.3.16
phosphatase H-II NARROW EC:3.1.3.16
phosphatase I NARROW EC:3.1.3.16
phosphatase IB NARROW EC:3.1.3.16
phosphatase II NARROW EC:3.1.3.16
phosphatase III NARROW EC:3.1.3.16
phosphatase IV NARROW EC:3.1.3.16
phosphatase SP NARROW EC:3.1.3.16
phosphopyruvate dehydrogenase phosphatase NARROW EC:3.1.3.16
phosphospectrin phosphatase NARROW EC:3.1.3.16
polycation modulated (PCM-) phosphatase NARROW EC:3.1.3.16
protein D phosphatase NARROW EC:3.1.3.16
protein phosphatase type 1 activity NARROW
protein phosphatase type 1, intrinsic catalyst activity NARROW
protein phosphatase type 2A activity NARROW
protein phosphatase type 2A, intrinsic catalyst activity NARROW
protein phosphatase type 2B activity NARROW
protein phosphatase type 2B, intrinsic catalyst activity NARROW
protein phosphatase type 2C activity NARROW
protein phosphatase type 4 activity NARROW
protein phosphatase type 4, intrinsic catalyst activity NARROW
protein phosphatase X NARROW
serine/threonine specific protein phosphatase activity EXACT
"calcineurin" NARROW []
"3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase" NARROW [EC:3.1.3.16]
"Aspergillus awamori acid protein phosphatase" NARROW [EC:3.1.3.16]
"BCKDH phosphatase" NARROW [EC:3.1.3.16]
"branched-chain alpha-keto acid dehydrogenase phosphatase" NARROW [EC:3.1.3.16]
"casein phosphatase" NARROW [EC:3.1.3.16]
"HMG-CoA reductase phosphatase" NARROW [EC:3.1.3.16]
"phosphatase 2A" NARROW [EC:3.1.3.16]
"phosphatase 2B" NARROW [EC:3.1.3.16]
"phosphatase C-II" NARROW [EC:3.1.3.16]
"phosphatase H-II" NARROW [EC:3.1.3.16]
"phosphatase I" NARROW [EC:3.1.3.16]
"phosphatase IB" NARROW [EC:3.1.3.16]
"phosphatase II" NARROW [EC:3.1.3.16]
"phosphatase III" NARROW [EC:3.1.3.16]
"phosphatase IV" NARROW [EC:3.1.3.16]
"phosphatase SP" NARROW [EC:3.1.3.16]
"phosphopyruvate dehydrogenase phosphatase" NARROW [EC:3.1.3.16]
"phosphospectrin phosphatase" NARROW [EC:3.1.3.16]
"polycation modulated (PCM-) phosphatase" NARROW [EC:3.1.3.16]
"protein D phosphatase" NARROW [EC:3.1.3.16]
"protein phosphatase type 1 activity" NARROW []
"protein phosphatase type 1, intrinsic catalyst activity" NARROW []
"protein phosphatase type 2A activity" NARROW []
"protein phosphatase type 2A, intrinsic catalyst activity" NARROW []
"protein phosphatase type 2B activity" NARROW []
"protein phosphatase type 2B, intrinsic catalyst activity" NARROW []
"protein phosphatase type 2C activity" NARROW []
"protein phosphatase type 4 activity" NARROW []
"protein phosphatase type 4, intrinsic catalyst activity" NARROW []
"protein phosphatase X" NARROW []
"serine/threonine specific protein phosphatase activity" EXACT []

Definition dbxrefs

Related dbxrefs
GO:0000158
GO:0000163
GO:0008598
GO:0008600
GO:0015071
GO:0030357
GO:0030358
GO:0030360
GO:0030361
Reactome:REACT_102328 "AMPK is dephosphorylated, Gallus gallus"
Reactome:REACT_103273 "AMPK is dephosphorylated, Danio rerio"
Reactome:REACT_104935 "multiphospho-CERT
Reactome:REACT_105168 "ERKs are inactivated by protein phosphatase 2A, Bos taurus"
Reactome:REACT_105744 "multiphospho-CERT
Reactome:REACT_106758 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Taeniopygia guttata"
Reactome:REACT_108076 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Sus scrofa"
Reactome:REACT_108095 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Danio rerio"
Reactome:REACT_109701 "AMPK is dephosphorylated, Caenorhabditis elegans"
Reactome:REACT_110128 "AMPK is dephosphorylated, Sus scrofa"
Reactome:REACT_111094 "PPA2A dephosphorylates SPRY2, Homo sapiens"
Reactome:REACT_112525 "PHLPP dephosphorylates S473 in AKT, Gallus gallus"
Reactome:REACT_112659 "AMPK is dephosphorylated, Saccharomyces cerevisiae"
Reactome:REACT_113935 "PHLPP dephosphorylates S473 in AKT, Xenopus tropicalis"
Reactome:REACT_114990 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Xenopus tropicalis"
Reactome:REACT_116150 "PP2B dephosphorylates DARPP-32 on T34, Rattus norvegicus"
Reactome:REACT_12403 "PHLPP dephosphorylates S473 in AKT, Homo sapiens"
Reactome:REACT_12539 "ERKs are inactivated by protein phosphatase 2A, Homo sapiens"
Reactome:REACT_15438 "DARPP-32 is dephosphorylated on Thr75 by PP2A, Homo sapiens"
Reactome:REACT_15494 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Homo sapiens"
Reactome:REACT_1705 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Rattus norvegicus"
Reactome:REACT_19304 "multiphospho-CERT
Reactome:REACT_21418 "AMPK is dephosphorylated, Homo sapiens"
Reactome:REACT_29362 "DARPP-32 is dephosphorylated on Thr75 by PP2A, Rattus norvegicus"
Reactome:REACT_30903 "DARPP-32 is dephosphorylated on Thr75 by PP2A, Canis familiaris"
Reactome:REACT_31424 "DARPP-32 is dephosphorylated on Thr75 by PP2A, Bos taurus"
Reactome:REACT_31944 "AMPK is dephosphorylated, Taeniopygia guttata"
Reactome:REACT_32258 "ERKs are inactivated by protein phosphatase 2A, Taeniopygia guttata"
Reactome:REACT_33433 "PHLPP dephosphorylates S473 in AKT, Rattus norvegicus"
Reactome:REACT_33609 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Mus musculus"
Reactome:REACT_403 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Homo sapiens"
Reactome:REACT_60521 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Sus scrofa"
Reactome:REACT_75794 "Decay of mRNA in SMG6
Reactome:REACT_77118 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Bos taurus"
Reactome:REACT_77285 "PHLPP dephosphorylates S473 in AKT, Drosophila melanogaster"
Reactome:REACT_77773 "multiphospho-CERT
Reactome:REACT_79893 "AMPK is dephosphorylated, Drosophila melanogaster"
Reactome:REACT_80418 "PHLPP dephosphorylates S473 in AKT, Taeniopygia guttata"
Reactome:REACT_81032 "ERKs are inactivated by protein phosphatase 2A, Dictyostelium discoideum"
Reactome:REACT_82252 "AMPK is dephosphorylated, Mus musculus"
Reactome:REACT_82455 "multiphospho-CERT
Reactome:REACT_82736 "ERKs are inactivated by protein phosphatase 2A, Mus musculus"
Reactome:REACT_82848 "multiphospho-CERT
Reactome:REACT_83123 "AMPK is dephosphorylated, Canis familiaris"
Reactome:REACT_84149 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Canis familiaris"
Reactome:REACT_84173 "AMPK is dephosphorylated, Rattus norvegicus"
Reactome:REACT_87477 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Xenopus tropicalis"
Reactome:REACT_87535 "multiphospho-CERT
Reactome:REACT_87738 "ERKs are inactivated by protein phosphatase 2A, Rattus norvegicus"
Reactome:REACT_89253 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Mus musculus"
Reactome:REACT_92068 "multiphospho-CERT
Reactome:REACT_92797 "AMPK is dephosphorylated, Xenopus tropicalis"
Reactome:REACT_93522 "multiphospho-CERT
Reactome:REACT_93551 "PHLPP dephosphorylates S473 in AKT, Mus musculus"
Reactome:REACT_93922 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Bos taurus"
Reactome:REACT_94309 "ERKs are inactivated by protein phosphatase 2A, Drosophila melanogaster"
Reactome:REACT_94590 "ERKs are inactivated by protein phosphatase 2A, Canis familiaris"
Reactome:REACT_94855 "PHLPP dephosphorylates S473 in AKT, Canis familiaris"
Reactome:REACT_95676 "multiphospho-CERT
Reactome:REACT_96055 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Danio rerio"
Reactome:REACT_96980 "DARPP-32 is dephosphorylated on Thr75 by PP2A, Mus musculus"
Reactome:REACT_98890 "phosphorylated perilipin + H2O -> perilipin + orthophosphate, Gallus gallus"

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