Term id	GO:0008545
Term name	JUN kinase kinase activity
Term definition	Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.
Comment

Synonyms
JNKK EXACT
"JNKK" EXACT []

Definition dbxrefs

Related dbxrefs
EC:2.7.11.-
Reactome:REACT_103413 "Phosphorylation of human JNKs by activated MKK4/MKK7, Danio rerio"
Reactome:REACT_112463 "Phosphorylation of human JNKs by activated MKK4/MKK7, Arabidopsis thaliana"
Reactome:REACT_114469 "Phosphorylation of human JNKs by activated MKK4/MKK7, Dictyostelium discoideum"
Reactome:REACT_114896 "Phosphorylation of human JNKs by activated MKK4/MKK7, Oryza sativa"
Reactome:REACT_29782 "Phosphorylation of human JNKs by activated MKK4/MKK7, Xenopus tropicalis"
Reactome:REACT_33106 "Phosphorylation of human JNKs by activated MKK4/MKK7, Taeniopygia guttata"
Reactome:REACT_6896 "Phosphorylation of human JNKs by activated MKK4/MKK7, Homo sapiens"
Reactome:REACT_80320 "Phosphorylation of human JNKs by activated MKK4/MKK7, Bos taurus"
Reactome:REACT_83873 "Phosphorylation of human JNKs by activated MKK4/MKK7, Gallus gallus"
Reactome:REACT_92449 "Phosphorylation of human JNKs by activated MKK4/MKK7, Canis familiaris"
Reactome:REACT_94164 "Phosphorylation of human JNKs by activated MKK4/MKK7, Sus scrofa"
Reactome:REACT_94971 "Phosphorylation of human JNKs by activated MKK4/MKK7, Mus musculus"
Reactome:REACT_95219 "Phosphorylation of human JNKs by activated MKK4/MKK7, Rattus norvegicus"
Reactome:REACT_99661 "Phosphorylation of human JNKs by activated MKK4/MKK7, Caenorhabditis elegans"

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