Forum Topic: MtDNA Mutation Screening

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MtDNA Mutation Screening

A cell contains many mitochondria, each having dozens of copies of the mitochondrial genome. The mutation rate of the mitochondrial genome is higher than that of the nuclear genome, which leads to heterogeneous populations of mitochondrial DNA in the same cell or even in the same mitochondria. When a cell divides, its mitochondria divide into two daughter cells. However, the separation process of mitochondria is random, and its tissue structure is much worse than the high-precision nuclear chromosome separation process during mitosis. The result is that the two daughter cells receive similar but not identical copies of mitochondrial DNA. [url][/url]

This topic was started by Joe Cohen.

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